CAR-T Cell Therapy

CARsgen Intellectual Properties


PhaseDisease TypeTherapy
Phase IHepatocellular carcinomaHumanized CAR-GPC3 T
Phase ISquamous lung cancerHumanized CAR-GPC3 T
Phase IPancreatic adenocarcinomaHumanized CAR-CLD18 T
Phase IGlioblastomaHumanized CAR-EGFR/EGFRvIII T
Phase IB-cell leukemia & LymphomaHumanized CAR-CD19 T
Phase IAdvanced gastric adenocarcinomaHumanized CAR-CLD18 T
Phase IMultiple myelomaHumanized CAR-BCMA T


Selected Publications
2017May 16Treatment of hepatocellular carcinoma with a GPC3-targeted bispecifc T cell engager
Yanyu Bi, Hua Jiang, Peng Wang, Bo Song, Huamao Wang, Xianming Kong, and Zonghai Li
2016Jan 19Treatment of solid tumors with chimeric antigen receptor-engineered T cells: current status and future prospects
Shengmeng Di & Zonghai L
2015Dec 14Adoptive immunotherapy using T lymphocytes redirected to glypican-3 for the treatment of lung squamous cell carcinoma
Kesang Li, Xiaorong Pan, Yanyu Bi, Wen Xu, Cheng Chen, Huiping Gao, Bizhi Shi, Hua Jiang, Shengli Yang, Liyan Jiang, Zonghai Li
2014Dec 15Development of T Cells Redirected to Glypican-3 for the Treatment of Hepatocellular Carcinoma
Huiping Gao, Kesang Li, Hong Tu, Xiaorong Pan, Hua Jiang, Bizhi Shi, Juan Kong, Hongyang Wang, Shengli Yang, Jianren Gu, and Zonghai Li
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